The second quarter effectively decided the match. Manchester scored six times - through Aaron Winstanley (2), Rob Simpson (2), Tom Hadley and Rob Rae - to two by the Scots, whose best efforts were thwarted by goalkeeper Ed Scott.
After labouring to a win over Caledonia on day one, Cheltenham outgunned Invicta 16-5, including four goals by Jake Vincent and three from Adam Legge.
Bristol were too strong for Team Northumbria, winning 17-7. Mark Thresher (4), Ryan Padbury (3) and Chris Taylor (3) led the scoring.